Product classification

HS code for Enzymes: 3507.90

Enzymes and prepared enzymes, other than rennet and concentrates thereof.

Classification of enzymes under HS 3507.90

The classification of enzymes under HS code 3507.90 is determined by the General Rules of Interpretation (GRI) and the specific notes of Chapter 35. Chapter 35 covers albuminoidal substances, modified starches, glues, and enzymes. Heading 3507 is specifically dedicated to enzymes and prepared enzymes that are not elsewhere specified or included in the nomenclature. Subheading 3507.90 serves as the residual category for all enzymes other than rennet and its concentrates. To be classified here, the product must be a protein substance that acts as a biological catalyst. This includes pure enzymes as well as prepared enzymes, which are enzymes with added substances like stabilizers, activators, or carriers, provided these additions do not transform the product into a medicament or a food preparation. The classification process requires verifying that the enzyme is not a culture of micro-organisms, which would instead fall under heading 3002. Furthermore, if the enzyme is put up in measured doses or packaged for retail sale for therapeutic use, it must be moved to Chapter 30. Industrial enzymes used in the textile, leather, and food industries are the primary occupants of this code.

Covers
  • Amylases and amylolytic preparations
  • Proteases (papain, bromelain, pepsin)
  • Lipases used in detergent manufacturing
  • Cellulases for textile processing
  • Glucose isomerase for high-fructose corn syrup production
  • Invertase and pectinases
Also under 3507.90
  • Novozymes Termamyl
  • DuPont Danisco GRINDAMYL
  • BASF Lavergy
  • AB Enzymes Veron
  • DSM Bakezyme

Codes often confused with 3507.90

Common mistake. Enzymes are frequently misclassified under heading 3004 (medicaments) when they are intended for health use but not yet packaged for retail sale. Conversely, they are often confused with heading 2934 for nucleic acids or heading 3002 for cultures of micro-organisms. It is critical to distinguish between the enzyme itself (3507.90) and the organism that produces it (3002.90).

30.04Medicaments; (not goods of heading no. 3002, 3005 or 3006) consisting of mixed or unmixed products for therapeutic or prophylactic use, put up in measured doses (incl. those in the form of transdermal admin. systems) or packed for retail sale29.34Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds30.02Human blood; animal blood for therapeutic, prophylactic or diagnostic uses; antisera, other blood fractions, immunological products, modified or obtained by biotechnological processes; vaccines, toxins, cultures of micro-organisms (excluding yeasts) etc3002.90Toxins, cultures of micro-organisms (excluding yeasts) and similar products

Top exporters and importers of HS 350790 (the code used for enzymes), 2025

In 2025, the largest exporter of HS 350790 (the code used for enzymes) in UN Comtrade data was Denmark, with 21% of world exports; the largest importer in UN Comtrade data was the Netherlands, with 13% of world imports. Countries that did not report 2025 data are estimated from partner records, which can understate them.

Figures cover everything classified under HS 350790, not only enzymes.

Top exporters 2025 · share of world exports

  1. 1 Denmark $1.7B
  2. 2 Netherlands $1.2B
  3. 3 United States $1.1B

World total: $8.1B Reported figures on UN Comtrade ↗

Top importers 2025 · share of world imports

  1. 1 Netherlands $1.1B
  2. 2 United States $949M
  3. 3 Germany $596M

World total: $8.2B Reported figures on UN Comtrade ↗

How these figures are built

109 countries reported 2025 trade to UN Comtrade in HS 2022, and their own totals are used. Countries that did not report are estimated from what other countries recorded trading with them. Those estimates miss trade with other non-reporting countries, so they can be low, and a non-reporting country can rank higher than shown or be missing from the list. World totals add both and leave out trade between two non-reporting countries. Figures are in current US dollars; reported imports are mostly valued CIF and exports FOB, and exports include re-exports. The UN Comtrade links show the underlying records; they can also list a few reporters left out here (regional groups and older HS editions).

Source: UN Comtrade (United Nations Statistics Division), 2025 annual data.

Brazil NCM codes for enzymes

Brazil splits HS 3507.90 into 15 NCM codes. Pick the one that matches your product:

Source: Siscomex NCM table, updated Oct 2026. The Portuguese text on each NCM page is the official one.

Questions about enzymes

What is the HS code for Enzymes?

The HS code for Enzymes is 350790 (Enzymes and prepared enzymes; other than rennet and concentrates thereof). The HS code for enzymes, other than rennet and its concentrates, is 3507.90.

How do I classify Enzymes for customs?

Enzymes is classified under HS code 350790 — Enzymes and prepared enzymes; other than rennet and concentrates thereof. This is a 6-digit subheading level code.

Are food-grade enzymes classified differently?

Generally, no; if they are prepared enzymes used as processing aids, they remain in 3507.90. However, if they are sold as finished food supplements, they may fall under 2106.90.

Which countries are the top exporters of enzymes (HS 350790)?

In 2025, the top exporters of HS 350790 (the code used for enzymes) in UN Comtrade data were Denmark ($1.7B, 21% of world exports), the Netherlands ($1.2B) and the United States ($1.1B). World exports came to about $8.1B, adding countries' reported figures and partner-based estimates for those that did not report (UN Comtrade data). Countries that did not report 2025 data are estimated from partner records, which can understate them.

Which countries are the top importers of enzymes (HS 350790)?

In 2025, the top importers of HS 350790 (the code used for enzymes) in UN Comtrade data were the Netherlands ($1.1B, 13% of world imports), the United States ($949M) and Germany ($596M). World imports came to about $8.2B, adding countries' reported figures and partner-based estimates for those that did not report (UN Comtrade data). Countries that did not report 2025 data are estimated from partner records, which can understate them.

Is the HS code for Enzymes the same in all countries?

The base HS code 350790 for Enzymes is internationally standardized for the first 6 digits across 200+ countries. Individual countries may add additional digits for national tariff lines and specific classifications.

What is the NCM code for enzymes in Brazil?

Brazil splits HS 350790 into 15 NCM codes, so the right one for enzymes depends on the product's details: 3507.90.11 (Alpha-amylase (Aspergillus oryzae)), 3507.90.19 (Other amylases and concentrates), 3507.90.21 (Fibrinucleases), 3507.90.22 (Bromelain), 3507.90.23 (Streptokinase), 3507.90.24 (Streptodornase), and more.