HS Code 35.07 – Enzymes; prepared enzymes not elsewhere specified or included

HS code 3507 is a 4-digit heading in the Harmonized System that covers: Enzymes; prepared enzymes not elsewhere specified or included. Heading 3507 covers enzymes and prepared enzymes not elsewhere specified or included. This classification encompasses both isolated, pure enzymes and enzyme preparations, which may contain diluents, carriers, or stabilizers to enhance their stability or activity. Enzymes are protein-based biological catalysts, and their classification here reflects their nature as albuminoidal substances within Chapter 35. The scope is broad, covering enzymes derived from various sources—animal, plant, or microbial—and used across a multitude of industries. Excluded are enzymes specifically put up as medicaments (Chapter 30) or as diagnostic reagents (Chapter 38). This heading is crucial for the food and beverage industry (e.g., baking, brewing, dairy), textiles (e.g., desizing), detergents (e.g., stain removal), pharmaceuticals (e.g., biocatalysis), and biotechnology (e.g., research, industrial bioprocesses). Accurate classification is essential for trade compliance, particularly regarding health and safety regulations, import/export controls, and potential tariff differentials based on origin or specific application. The increasing use of enzymes in sustainable industrial processes highlights their growing trade significance.

Amylases, proteases (e.g., trypsin, papain, bromelain), lipases, cellulases, lactase, pectinases, glucose isomerase, rennet (chymosin), catalase, urease, phytase, DNA polymerase, restriction enzymes, enzyme mixtures for detergents, baking enzymes, brewing enzymes, textile desizing enzymes, feed enzymes, industrial enzymes, food-grade enzymes, pharmaceutical-grade enzymes, laboratory enzymes, xylanases, glucoamylases, invertase, lipase preparations, protease preparations, cellulase preparations.

Common misclassifications include confusing enzymes put up as medicaments (HS 3004) or diagnostic reagents (HS 3822) with those classified under 3507. The key distinction lies in the explicit therapeutic, prophylactic, or diagnostic presentation and purpose. Another error is classifying pure amino acids (HS 2922) or other protein substances (HS 3504) as enzymes; enzymes are specific proteins with catalytic activity. The 'prepared' aspect is also important; raw, unprocessed biological materials containing enzymes might fall elsewhere if not specifically isolated or concentrated as an enzyme preparation.

In 2025, the top exporters of HS code 3507 in UN Comtrade data were Denmark ($1.8B, 22% of world exports), the Netherlands ($1.2B) and the United States ($1.1B). World exports came to about $8.3B, adding countries' reported figures and partner-based estimates for those that did not report (UN Comtrade data). Countries that did not report 2025 data are estimated from partner records, which can understate them.

In 2025, the top importers of HS code 3507 in UN Comtrade data were the Netherlands ($1.1B, 13% of world imports), the United States ($960M) and Germany ($602M). World imports came to about $8.4B, adding countries' reported figures and partner-based estimates for those that did not report (UN Comtrade data). Countries that did not report 2025 data are estimated from partner records, which can understate them.

HS code 3507 is a 4-digit heading under Chapter 35 of the Harmonized System. The first 2 digits (35) identify the chapter, and digits 3-4 (07) specify the heading. This code contains multiple 6-digit subheadings for precise product classification.