HS code · 6-digit subheading

HS Code 2922.49 – Amino-acids, other than those containing more than one kind of oxygen function, their esters; salts thereof, excluding lysine, glutamic acid, anthranalic acid and tilidine, their esters and salts thereof

HS code 2922.49 is the 6-digit subheading for amino-acids, other than those containing more than one kind of oxygen function, their esters, salts thereof, excluding lysine, glutamic acid, anthranalic acid and tilidine, their esters and salts thereof. It is used for glycine, L-Alanine, L-Valine, L-Leucine and L-Isoleucine.

What HS 2922.49 covers

This broad residual HS code covers "other" amino acids, their esters, and salts, provided they do not contain more than one type of oxygen function, and explicitly excludes lysine, glutamic acid, anthranilic acid, and tilidine, which have their own specific subheadings. This category includes a vast array of amino acids, both proteinogenic and non-proteinogenic, that serve diverse functions across various industries. In international trade, these compounds are imported by pharmaceutical companies for drug synthesis, by the food and beverage industry for nutritional supplements and flavorings, by cosmetic manufacturers, and by research institutions. Exporters are typically specialty chemical manufacturers and biochemical companies worldwide. Key considerations for trade include the high purity requirements for pharmaceutical and food-grade applications, specific enantiomeric forms (L- or D-), and compliance with various industry-specific regulations. The market is highly fragmented, driven by specialized applications and ongoing research in biotechnology and medicine, making it a dynamic sector.

Covers
  • Glycine
  • L-Alanine
  • L-Valine
  • L-Leucine
  • L-Isoleucine
  • L-Proline
  • L-Serine
  • L-Threonine
  • L-Cysteine
  • L-Methionine
  • L-Aspartic Acid
  • L-Arginine
  • L-Histidine
  • L-Phenylalanine
  • L-Tyrosine
  • L-Tryptophan
Examples
  • Ajinomoto L-Alanine
  • Kyowa Hakko L-Arginine
  • Evonik L-Threonine
  • Sigma-Aldrich Glycine
  • NOW Foods L-Tryptophan

Codes often confused with 2922.49

Common mistake. This code is a "basket" category for amino acids not specifically listed elsewhere in 2922.41 through 2922.44. Misclassification often occurs if one of the specifically enumerated amino acids (lysine, glutamic acid, anthranilic acid, tilidine) is incorrectly placed here, or if an amino acid derivative contains multiple oxygen functions, leading to 292250.

Top exporters and importers of HS code 292249, 2025

In 2025, the largest exporter of HS code 292249 in UN Comtrade data was China, with 39% of world exports; the largest importer in UN Comtrade data was the United States, with 16% of world imports. Countries that did not report 2025 data are estimated from partner records, which can understate them.

Top exporters 2025 · share of world exports

  1. 1 China $1.5B
  2. 2 Singapore $375M
  3. 3 Germany $335M

World total: $4.0B Reported figures on UN Comtrade ↗

Top importers 2025 · share of world imports

  1. 1 United States $713M
  2. 2 Germany $420M
  3. 3 Belgium $249M

World total: $4.4B Reported figures on UN Comtrade ↗

How these figures are built

109 countries reported 2025 trade to UN Comtrade in HS 2022, and their own totals are used. Countries that did not report are estimated from what other countries recorded trading with them. Those estimates miss trade with other non-reporting countries, so they can be low, and a non-reporting country can rank higher than shown or be missing from the list. World totals add both and leave out trade between two non-reporting countries. Figures are in current US dollars; reported imports are mostly valued CIF and exports FOB, and exports include re-exports. The UN Comtrade links show the underlying records; they can also list a few reporters left out here (regional groups and older HS editions).

Source: UN Comtrade (United Nations Statistics Division), 2025 annual data.

Brazil NCM codes for 2922.49 14

Brazil splits HS 2922.49 into 14 NCM codes, Mercosur's 8-digit tariff lines.

  1. 2922.49.10 Glycine and its saltsGlicina e seus sais
  2. 2922.49.20 Ethylenediaminetetraacetic acid (EDTA) and saltsÁcido etilenodiaminotetracético (EDTA) e seus sais
  3. 2922.49.3 Iminodiacetic acid and its saltsÁcido iminodiacético e seus sais Group
  4. 2922.49.31 Iminodiacetic acidÁcido iminodiacético
  5. 2922.49.32 Iminodiacetic acid saltsSais
  6. 2922.49.40 Diethylenetriaminepentaacetic acid (DTPA), saltsÁcido dietilenotriaminopentacético e seus sais
  7. 2922.49.5 alpha-Phenylglycine and its salts; derivatives thereofalfa-Fenilglicina e seus sais; derivados destes produtos Group
  8. 2922.49.51 Alpha-phenylglycinealfa-Fenilglicina
  9. 2922.49.52 D(-)-Phenylglycyl chloride hydrochlorideCloridrato de cloreto de D(-)alfa-aminobenzenoacetila
  10. 2922.49.59 Other alpha-phenylglycine derivatives and saltsOutros
  11. 2922.49.6 Diclofenac and its salts; derivatives thereofDiclofenaco e seus sais; derivados destes produtos Group
  12. 2922.49.61 Diclofenac sodiumDiclofenaco de sódio
  13. 2922.49.62 Diclofenac potassiumDiclofenaco de potássio
  14. 2922.49.63 Diclofenac diethylammoniumDiclofenaco de dietilamônio
  15. 2922.49.64 DiclofenacDiclofenaco
  16. 2922.49.69 Other diclofenac salts and derivativesOutros
  17. 2922.49.90 Other amino-acids and their esters; saltsOutros

All Brazil NCM codes in heading 29.22 →

Source: Siscomex NCM table, updated Oct 2026. The Portuguese text is official; the English is our translation.

Questions about HS 2922.49

What is HS code 292249?

HS code 292249 is a 6-digit subheading in the Harmonized System that covers: Amino-acids, other than those containing more than one kind of oxygen function, their esters; salts thereof, excluding lysine, glutamic acid, anthranalic acid and tilidine, their esters and salts thereof. This broad residual HS code covers "other" amino acids, their esters, and salts, provided they do not contain more than one type of oxygen function, and explicitly excludes lysine, glutamic acid, anthranilic acid, and tilidine, which have their own specific subheadings. This category includes a vast array of amino acids, both proteinogenic and non-proteinogenic, that serve diverse functions across various industries. In international trade, these compounds are imported by pharmaceutical companies for drug synthesis, by the food and beverage industry for nutritional supplements and flavorings, by cosmetic manufacturers, and by research institutions. Exporters are typically specialty chemical manufacturers and biochemical companies worldwide. Key considerations for trade include the high purity requirements for pharmaceutical and food-grade applications, specific enantiomeric forms (L- or D-), and compliance with various industry-specific regulations. The market is highly fragmented, driven by specialized applications and ongoing research in biotechnology and medicine, making it a dynamic sector.

What products fall under HS code 292249?

Glycine, L-Alanine, L-Valine, L-Leucine, L-Isoleucine, L-Proline, L-Serine, L-Threonine, L-Cysteine, L-Methionine, L-Aspartic Acid, L-Arginine, L-Histidine, L-Phenylalanine, L-Tyrosine, L-Tryptophan

What are common misclassifications for HS code 292249?

This code is a "basket" category for amino acids not specifically listed elsewhere in 2922.41 through 2922.44. Misclassification often occurs if one of the specifically enumerated amino acids (lysine, glutamic acid, anthranilic acid, tilidine) is incorrectly placed here, or if an amino acid derivative contains multiple oxygen functions, leading to 292250.

Which countries are the top exporters of goods under HS code 292249?

In 2025, the top exporters of HS code 292249 in UN Comtrade data were China ($1.5B, 39% of world exports), Singapore ($375M) and Germany ($335M). World exports came to about $4.0B, adding countries' reported figures and partner-based estimates for those that did not report (UN Comtrade data). Countries that did not report 2025 data are estimated from partner records, which can understate them.

Which countries are the top importers of goods under HS code 292249?

In 2025, the top importers of HS code 292249 in UN Comtrade data were the United States ($713M, 16% of world imports), Germany ($420M) and Belgium ($249M). World imports came to about $4.4B, adding countries' reported figures and partner-based estimates for those that did not report (UN Comtrade data). Countries that did not report 2025 data are estimated from partner records, which can understate them.

How is HS code 292249 structured?

HS code 292249 is a 6-digit subheading under the Harmonized System. The first 2 digits (29) identify the chapter, digits 3-4 (22) identify the heading, and digits 5-6 (49) specify the subheading. This code is standardized globally by the World Customs Organization.

What is the Brazil NCM code for HS code 292249?

Brazil splits HS code 292249 into 14 NCM codes: 2922.49.10 (Glycine and its salts), 2922.49.20 (Ethylenediaminetetraacetic acid (EDTA) and salts), 2922.49.31 (Iminodiacetic acid), 2922.49.32 (Iminodiacetic acid salts), 2922.49.40 (Diethylenetriaminepentaacetic acid (DTPA), salts), 2922.49.51 (Alpha-phenylglycine), 2922.49.52 (D(-)-Phenylglycyl chloride hydrochloride), 2922.49.59 (Other alpha-phenylglycine derivatives and salts), and more listed on this page. The first 6 digits of each match the HS code.