HS Code 29.22 – Oxygen-function amino-compounds

HS code 2922 is a 4-digit heading in the Harmonized System that covers: Oxygen-function amino-compounds. Heading 2922 covers 'Oxygen-function amino-compounds,' a complex and vital category within Chapter 29 of the Harmonized System. This classification encompasses organic compounds containing both an amino-function and an oxygen-function (e.g., hydroxyl, ether, aldehyde, ketone, carboxyl group) within the same molecule, provided they are not specifically excluded elsewhere. Key sub-categories include amino-alcohols (like monoethanolamine), amino-phenols, amino-ethers, amino-aldehydes, amino-ketones, and amino-acids (excluding those of 2923). This heading is critical for distinguishing these bifunctional compounds from simpler amines (2921) or compounds with only oxygen functions. The scope is broad, capturing a vast array of compounds essential for pharmaceuticals (e.g., amino acids, epinephrine), food additives (e.g., glutamic acid), cosmetics, agrochemicals, and industrial processes. Proper classification under 2922 is paramount for trade compliance, affecting tariff rates, regulatory approvals (especially for food and pharma ingredients), and customs clearance. Historically, the isolation and synthesis of amino acids and amino alcohols have been foundational to biochemistry and synthetic organic chemistry, driving advancements in medicine and nutrition. Its placement within Chapter 29 highlights its identity as a chemically defined organic compound, distinct from mixtures or biological preparations, underscoring its role as a fundamental building block in global trade.

Monoethanolamine, Diethanolamine, Triethanolamine, Choline, L-Tyrosine, L-Tryptophan, L-Phenylalanine, L-Glutamic acid, L-Lysine, Glycine, L-Alanine, L-Valine, L-Methionine, L-Cysteine, L-Serine, L-Threonine, L-Aspartic acid, L-Proline, Epinephrine (Adrenaline), Norepinephrine, Dopamine, Salbutamol, Levodopa, Hydroxyproline

Misclassification under 2922 is common due to the dual functionality requirement. Traders often mistakenly classify compounds with only an amino group under 2922 instead of 2921, or vice versa, if the presence of an oxygen function is overlooked. Another frequent error is confusing amino acids with peptides or proteins, which fall under Chapter 35 (Albuminoidal substances; modified starches; glues; enzymes). Similarly, if the amino and oxygen functions are part of a heterocyclic ring system, the compound might belong to 2933 or 2934, not 2922. For instance, specific amino-phospholipids should be classified under 2923, not 2922.

In 2025, the top exporters of HS code 2922 in UN Comtrade data were China ($5.8B, 41% of world exports), the United States ($1.0B) and Germany ($971M). World exports came to about $14.0B, adding countries' reported figures and partner-based estimates for those that did not report (UN Comtrade data). Countries that did not report 2025 data are estimated from partner records, which can understate them.

In 2025, the top importers of HS code 2922 in UN Comtrade data were the United States ($1.5B, 9.8% of world imports), Germany ($1.1B) and India ($845M). World imports came to about $15.4B, adding countries' reported figures and partner-based estimates for those that did not report (UN Comtrade data). Countries that did not report 2025 data are estimated from partner records, which can understate them.

HS code 2922 is a 4-digit heading under Chapter 29 of the Harmonized System. The first 2 digits (29) identify the chapter, and digits 3-4 (22) specify the heading. This code contains multiple 6-digit subheadings for precise product classification.